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BDBM50073922 CHEMBL86313::{(S)-1-[(7-Bromo-2,3-dioxo-1,2,3,4-tetrahydro-quinoxalin-5-ylmethyl)-amino]-ethyl}-phosphonic acid

SMILES: C[C@@H](NCc1cc(Br)cc2[nH]c(=O)c(=O)[nH]c12)P(O)(O)=O

InChI Key: InChIKey=DPFHVUSPVHRVFL-YFKPBYRVSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50073922   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(Homo sapiens (Human))
BDBM50073922
PNG
(CHEMBL86313 | {(S)-1-[(7-Bromo-2,3-dioxo-1,2,3,4-t...)
Show SMILES C[C@@H](NCc1cc(Br)cc2[nH]c(=O)c(=O)[nH]c12)P(O)(O)=O
Show InChI InChI=1S/C11H13BrN3O5P/c1-5(21(18,19)20)13-4-6-2-7(12)3-8-9(6)15-11(17)10(16)14-8/h2-3,5,13H,4H2,1H3,(H,14,16)(H,15,17)(H2,18,19,20)/t5-/m0/s1
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PC sid
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Similars

Article
PubMed
n/an/a 5n/an/an/an/an/an/a



University Hospital Zurich

Curated by ChEMBL


Assay Description
Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]-MDL-105,519 bin...


Bioorg Med Chem Lett 10: 75-8 (2000)


Article DOI: 10.1016/s0960-894x(99)00576-4
BindingDB Entry DOI: 10.7270/Q2M907WV
More data for this
Ligand-Target Pair