BDBM50074309 1-(2,4-Dichloro-phenyl)-4-methyl-5-phenyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide::CHEMBL285153

SMILES Cc1c(nn(c1-c1ccccc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1

InChI Key InChIKey=ORFZPLKMZALKSH-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50074309   

TargetCannabinoid receptor 1(Rat)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50074309(1-(2,4-Dichloro-phenyl)-4-methyl-5-phenyl-1H-pyraz...)
Affinity DataKi:  123nMAssay Description:Inhibition of [3H]CP-55940 binding to cannabinoid receptor 1 in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)TBA
LigandPNGBDBM50074309(1-(2,4-Dichloro-phenyl)-4-methyl-5-phenyl-1H-pyraz...)
Affinity DataKi:  123nMAssay Description:Antagonist activity at CB1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetCannabinoid receptor 1(Rat)
University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50074309(1-(2,4-Dichloro-phenyl)-4-methyl-5-phenyl-1H-pyraz...)
Affinity DataKi:  123nMAssay Description:Binding affinity against Cannabinoid receptor 1 in rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)TBA
LigandPNGBDBM50074309(1-(2,4-Dichloro-phenyl)-4-methyl-5-phenyl-1H-pyraz...)
Affinity DataKi:  123nMAssay Description:Antagonist activity at CB1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetCannabinoid receptor 2(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50074309(1-(2,4-Dichloro-phenyl)-4-methyl-5-phenyl-1H-pyraz...)
Affinity DataKi:  217nMAssay Description:Binding affinity against Cannabinoid receptor 2 in mouse spleenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed