BindingDB logo
myBDB logout

BDBM50074407 (Butyl-{4-[(4-dimethylamino-2-methyl-phenyl)-ethyl-amino]-6-methyl-[1,3,5]triazin-2-yl}-amino)-acetonitrile::CHEMBL442773

SMILES: CCCCN(CC#N)c1nc(C)nc(n1)N(CC)c1ccc(cc1C)N(C)C

InChI Key: InChIKey=AZAKRKXETQZRBN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074407   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50074407
PNG
((Butyl-{4-[(4-dimethylamino-2-methyl-phenyl)-ethyl...)
Show SMILES CCCCN(CC#N)c1nc(C)nc(n1)N(CC)c1ccc(cc1C)N(C)C
Show InChI InChI=1S/C21H31N7/c1-7-9-13-27(14-12-22)20-23-17(4)24-21(25-20)28(8-2)19-11-10-18(26(5)6)15-16(19)3/h10-11,15H,7-9,13-14H2,1-6H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
8n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity for human recombinant corticotropin releasing factor receptor 1


J Med Chem 42: 805-18 (1999)


Article DOI: 10.1021/jm980222w
BindingDB Entry DOI: 10.7270/Q29S1Q63
More data for this
Ligand-Target Pair