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BDBM50074433 1-(4-Isopropyl-phenyl)-4,6-dimethyl-1H-pyrrolo[2,3-b]pyridine::CHEMBL415752

SMILES: CC(C)c1ccc(cc1)-n1ccc2c(C)cc(C)nc12

InChI Key: InChIKey=PCFKEZPOCNMGNB-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074433   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50074433
PNG
(1-(4-Isopropyl-phenyl)-4,6-dimethyl-1H-pyrrolo[2,3...)
Show SMILES CC(C)c1ccc(cc1)-n1ccc2c(C)cc(C)nc12
Show InChI InChI=1S/C18H20N2/c1-12(2)15-5-7-16(8-6-15)20-10-9-17-13(3)11-14(4)19-18(17)20/h5-12H,1-4H3
PDB
MMDB

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PC sid
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Similars

Article
PubMed
2.46E+3n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity was determined against corticotropin releasing factor receptor 1


J Med Chem 42: 819-32 (1999)


Article DOI: 10.1021/jm980223o
BindingDB Entry DOI: 10.7270/Q22V2GT5
More data for this
Ligand-Target Pair