BDBM50074746 3-(3-Chloro-phenyl)-5,7-dimethoxy-chromen-4-one::CHEMBL7981

SMILES COc1cc(OC)c2c(c1)occ(-c1cccc(Cl)c1)c2=O

InChI Key InChIKey=USNKYQXLHXAMIJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50074746   

TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Novartis

Curated by ChEMBL
LigandPNGBDBM50074746(3-(3-Chloro-phenyl)-5,7-dimethoxy-chromen-4-one | ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Mus musculus)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074746(3-(3-Chloro-phenyl)-5,7-dimethoxy-chromen-4-one | ...)
Affinity DataIC50:  4.62E+4nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis

Curated by ChEMBL
LigandPNGBDBM50074746(3-(3-Chloro-phenyl)-5,7-dimethoxy-chromen-4-one | ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis

Curated by ChEMBL
LigandPNGBDBM50074746(3-(3-Chloro-phenyl)-5,7-dimethoxy-chromen-4-one | ...)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed