BDBM50074779 CHEMBL10303::[2-Phenyl-4-((R)-1-phenyl-propylcarbamoyl)-quinolin-3-yloxy]-acetic acid

SMILES CC[C@@H](NC(=O)c1c(OCC(O)=O)c(nc2ccccc12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=RJIWGNBRTQFKBW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074779   

TargetNeuromedin-K receptor(Human)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50074779([2-Phenyl-4-((R)-1-phenyl-propylcarbamoyl)-quinoli...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50074779([2-Phenyl-4-((R)-1-phenyl-propylcarbamoyl)-quinoli...)
Affinity DataKi:  214nMAssay Description:Binding affinity towards cloned human Tachykinin receptor 2 (hNK-2) expressed in CHO cells using [125I][MePhe7]-NKBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50074779([2-Phenyl-4-((R)-1-phenyl-propylcarbamoyl)-quinoli...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards cloned human Tachykinin receptor 1 (hNK-1) expressed in CHO cells using [125I][MePhe7]-NKBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed