BDBM50074808 2-Phenyl-quinoline-4-carboxylic acid (2,2,2-trifluoro-1-phenyl-ethyl)-amide::CHEMBL275316

SMILES FC(F)(F)C(NC(=O)c1cc(nc2ccccc12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=ZSLSSZDNNDSSEF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50074808   

TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50074808(2-Phenyl-quinoline-4-carboxylic acid (2,2,2-triflu...)
Affinity DataKi:  454nMAssay Description:Binding affinity towards cloned human Tachykinin receptor 3 (hNK-3) expressed in CHO cells using [125I][MePhe7]-NKBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50074808(2-Phenyl-quinoline-4-carboxylic acid (2,2,2-triflu...)
Affinity DataKi:  501nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50074808(2-Phenyl-quinoline-4-carboxylic acid (2,2,2-triflu...)
Affinity DataKi:  501nMAssay Description:Binding affinity to human NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed