BDBM50074922 (+-)-2-fluoro-alpha-methyl-4-biphenylacetic acid::2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid::2-(2-fluorobiphenyl-4-yl)propanoic acid::2-fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic acid::3-fluoro-4-phenylhydratropic acid::Ansaid::CHEMBL563::FLURBIPROFEN::US9630914, Compound A

SMILES: CC(C(O)=O)c1ccc(c(F)c1)-c1ccccc1

InChI Key: InChIKey=SYTBZMRGLBWNTM-UHFFFAOYSA-N

Data: 11 KI  31 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 42 hits for monomerid = 50074922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldo-keto reductase family 1 member C4 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Aldo-keto reductase family 1 member C3 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C1 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C4 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B1 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member B10 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mouse)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C2 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C1 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C2 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C3 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 6 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rat)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acid-sensing ion channel 3 (Rat)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.29E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile salt export pump (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acid-sensing ion channel 1 (Rat)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Rat)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fatty acid-binding protein, liver (Rat)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		4.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fatty acid-binding protein, intestinal (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.32E+4	-12.0	n/a	n/a	n/a	n/a	n/a	n/a	293.15
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fatty acid-binding protein, intestinal (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Fatty acid-binding protein, liver (Rat)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.22E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Albumin (Human)	BDBM50074922 (2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid | ...) Show SMILES Show InChI	GoogleScholar	UniChem		3.31E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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