BDBM50075055 ((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R,3S,4R,5R)-3,4-dihydroxy-5-{4-[2-(4-phenoxy-phenyl)-ethyl]-thiazol-2-yl}-tetrahydro-furan-2-ylmethyl ester::CHEMBL341331

SMILES CC(C)C[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)c1nc(CCc2ccc(Oc3ccccc3)cc2)cs1

InChI Key InChIKey=FREGHQKQLWGWHX-UDEADWOUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075055   

TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075055(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  100nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075055(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  6nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075055(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)
Affinity DataIC50:  1.15E+3nMAssay Description:Compound tested for the inhibition of human Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed