BDBM50075315 5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(4-trifluoromethyl-benzyl)-benzamide::5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(4-trifluoromethyl-benzyl)-benzamide(KRP297)::CHEMBL24458::KRP-297

SMILES: COc1ccc(Cc2sc(=O)[nH]c2O)cc1C(=O)NCc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=SUYNESVDWLCJSR-UHFFFAOYSA-N

Data: 2 KI  2 IC50  4 Kd  22 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50075315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	850	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	914	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	922	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	463	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	83	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Mouse)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Mouse)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	850	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Mouse)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	326	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50075315 (5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...) Show SMILES Show InChI	GoogleScholar	UniChem		330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair