BDBM50075326 4-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dione::CHEMBL315471

SMILES Cc1cccc(C)c1N1C(=O)c2cccc(N)c2C1=O

InChI Key InChIKey=IANBVEOEWQXOQJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50075326   

TargetAminopeptidase N(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075326(4-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dion...)
Affinity DataIC50:  1.09E+5nMAssay Description:Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075326(4-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dion...)
Affinity DataIC50:  1.08E+5nMAssay Description:Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075326(4-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dion...)
Affinity DataIC50: >3.75E+5nMAssay Description:Inhibitory activity against aminopeptidase N assayed by the L-Ala-MCA method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075326(4-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dion...)
Affinity DataIC50:  6.01E+4nMAssay Description:Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075326(4-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dion...)
Affinity DataIC50: >3.75E+5nMAssay Description:Inhibitory activity against dipeptidyl peptidase IV (DPP- IV)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075326(4-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dion...)
Affinity DataIC50:  6.01E+4nMAssay Description:Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed