BDBM50075328 2-(2,6-Diisopropyl-phenyl)-5-hydroxy-isoindole-1,3-dione::2-(2,6-diisopropylphenyl)-5-hydroxyisoindoline-1,3-dione::CHEMBL313952

SMILES CC(C)c1cccc(C(C)C)c1N1C(=O)c2ccc(O)cc2C1=O

InChI Key InChIKey=LAKWINYVWJPHQW-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50075328   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075328(2-(2,6-Diisopropyl-phenyl)-5-hydroxy-isoindole-1,3...)
Affinity DataIC50:  6.59E+4nMAssay Description:Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075328(2-(2,6-Diisopropyl-phenyl)-5-hydroxy-isoindole-1,3...)
Affinity DataIC50:  6.59E+4nMAssay Description:Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075328(2-(2,6-Diisopropyl-phenyl)-5-hydroxy-isoindole-1,3...)
Affinity DataIC50:  4.64E+4nMAssay Description:Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075328(2-(2,6-Diisopropyl-phenyl)-5-hydroxy-isoindole-1,3...)
Affinity DataIC50:  4.63E+4nMAssay Description:Inhibitory activity against aminopeptidase N assayed by the L-Ala-MCA method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Sus scrofa)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075328(2-(2,6-Diisopropyl-phenyl)-5-hydroxy-isoindole-1,3...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of tubulin polymerization in porcine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075328(2-(2,6-Diisopropyl-phenyl)-5-hydroxy-isoindole-1,3...)
Affinity DataIC50:  6.49E+4nMAssay Description:Inhibitory activity against dipeptidyl peptidase IV (DPP- IV)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50075328(2-(2,6-Diisopropyl-phenyl)-5-hydroxy-isoindole-1,3...)
Affinity DataIC50:  4.64E+4nMAssay Description:Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed