BDBM50075525 4-[5-(2-Amino-ethylsulfanyl)-[1,3,4]thiadiazol-2-yl]-2,6-di-tert-butyl-phenol::CHEMBL274271

SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)-c1nnc(SCCN)s1

InChI Key InChIKey=AKGGOFKXDGINAT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075525   

TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075525(4-[5-(2-Amino-ethylsulfanyl)-[1,3,4]thiadiazol-2-y...)
Affinity DataIC50: 2.00E+4nMAssay Description:IC50 value against Prostaglandin G/H synthase 1 of human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075525(4-[5-(2-Amino-ethylsulfanyl)-[1,3,4]thiadiazol-2-y...)
Affinity DataIC50: 3.60E+4nMAssay Description:IC50 value against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075525(4-[5-(2-Amino-ethylsulfanyl)-[1,3,4]thiadiazol-2-y...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed