BDBM50075535 2,6-Di-tert-butyl-4-(5-ethylsulfanyl-[1,3,4]thiadiazol-2-yl)-phenol::CHEMBL279801

SMILES CCSc1nnc(s1)-c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI Key InChIKey=XYNOMYGVSOXKJX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075535   

TargetProstaglandin G/H synthase 2(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075535(2,6-Di-tert-butyl-4-(5-ethylsulfanyl-[1,3,4]thiadi...)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075535(2,6-Di-tert-butyl-4-(5-ethylsulfanyl-[1,3,4]thiadi...)
Affinity DataIC50: 180nMAssay Description:IC50 value against Prostaglandin G/H synthase 2 of murine J774A.1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075535(2,6-Di-tert-butyl-4-(5-ethylsulfanyl-[1,3,4]thiadi...)
Affinity DataIC50: 3.10E+3nMAssay Description:IC50 value against Prostaglandin G/H synthase 1 of human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075535(2,6-Di-tert-butyl-4-(5-ethylsulfanyl-[1,3,4]thiadi...)
Affinity DataIC50: 1.00E+5nMAssay Description:IC50 value against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed