BDBM50075537 2,6-Di-tert-butyl-4-(5-ethanesulfinyl-[1,3,4]thiadiazol-2-yl)-phenol::CHEMBL16843

SMILES CCS(=O)c1nnc(s1)-c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI Key InChIKey=CHEJRRFLVQYEME-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075537   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075537(2,6-Di-tert-butyl-4-(5-ethanesulfinyl-[1,3,4]thiad...)
Affinity DataIC50: >2.00E+4nMAssay Description:IC50 value against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075537(2,6-Di-tert-butyl-4-(5-ethanesulfinyl-[1,3,4]thiad...)
Affinity DataIC50:  230nMAssay Description:IC50 value against Prostaglandin G/H synthase 2 of murine J774A.1 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075537(2,6-Di-tert-butyl-4-(5-ethanesulfinyl-[1,3,4]thiad...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075537(2,6-Di-tert-butyl-4-(5-ethanesulfinyl-[1,3,4]thiad...)
Affinity DataIC50:  1.46E+4nMAssay Description:IC50 value against Prostaglandin G/H synthase 1 of human platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed