BDBM50075541 4,6-Di-tert-butyl-2-(5-ethylsulfanyl-[1,3,4]thiadiazol-2-yl)-pyrimidin-5-ol::CHEMBL17218

SMILES CCSc1nnc(s1)-c1nc(c(O)c(n1)C(C)(C)C)C(C)(C)C

InChI Key InChIKey=UXJLZLPNHILXSE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075541   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075541(4,6-Di-tert-butyl-2-(5-ethylsulfanyl-[1,3,4]thiadi...)
Affinity DataIC50:  680nMAssay Description:IC50 value against Prostaglandin G/H synthase 1 of human platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075541(4,6-Di-tert-butyl-2-(5-ethylsulfanyl-[1,3,4]thiadi...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075541(4,6-Di-tert-butyl-2-(5-ethylsulfanyl-[1,3,4]thiadi...)
Affinity DataIC50:  18nMAssay Description:IC50 value against Prostaglandin G/H synthase 2 of murine J774A.1 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed