BDBM50075544 CHEMBL16826::N-[5-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-[1,3,4]thiadiazol-2-yl]-guanidine

SMILES [#6]C([#6])([#6])c1cc(cc(c1-[#8])C([#6])([#6])[#6])-c1nnc(\[#7]=[#6](\[#7])-[#7])s1

InChI Key InChIKey=DYTPSJWZDQFGPV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075544   

TargetProstaglandin G/H synthase 2(Mouse)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075544(N-[5-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-[1,3,4]t...)
Affinity DataIC50: 210nMAssay Description:IC50 value against Prostaglandin G/H synthase 2 of murine J774A.1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075544(N-[5-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-[1,3,4]t...)
Affinity DataIC50: 2.80E+3nMAssay Description:IC50 value against Prostaglandin G/H synthase 1 of human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075544(N-[5-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-[1,3,4]t...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075544(N-[5-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-[1,3,4]t...)
Affinity DataIC50: 8.80E+4nMAssay Description:IC50 value against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed