BDBM50075547 2,6-Di-tert-butyl-4-(5-hydrazino-[1,3,4]thiadiazol-2-yl)-phenol::CHEMBL16891

SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)-c1nnc(NN)s1

InChI Key InChIKey=AHIOUXABOCYPEI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075547   

TargetProstaglandin G/H synthase 2(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075547(2,6-Di-tert-butyl-4-(5-hydrazino-[1,3,4]thiadiazol...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075547(2,6-Di-tert-butyl-4-(5-hydrazino-[1,3,4]thiadiazol...)
Affinity DataIC50: 3.20E+3nMAssay Description:IC50 value against Prostaglandin G/H synthase 1 of human platelet rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075547(2,6-Di-tert-butyl-4-(5-hydrazino-[1,3,4]thiadiazol...)
Affinity DataIC50: 3.70E+3nMAssay Description:IC50 value against Prostaglandin G/H synthase 2 of murine J774A.1 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075547(2,6-Di-tert-butyl-4-(5-hydrazino-[1,3,4]thiadiazol...)
Affinity DataIC50: 1.70E+4nMAssay Description:IC50 value against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed