BDBM50075653 2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone::CHEMBL22812

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccc(F)cc1

InChI Key InChIKey=WVMKHZFGKXZRFP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075653   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075653(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-c...)
Affinity DataIC50: 19nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075653(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-c...)
Affinity DataIC50: 80nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075653(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-c...)
Affinity DataIC50: 500nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075653(2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-c...)
Affinity DataIC50: 3.70E+3nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 (hCOX-1) in the human whole blood assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed