BDBM50075659 2-(3,3-Dimethyl-but-1-ynyl)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone::CHEMBL436539

SMILES CC(C)(C)C#CC1=C(CCC1=O)c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=FCLFZNWXLWQMDF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075659   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075659(2-(3,3-Dimethyl-but-1-ynyl)-3-(4-methanesulfonyl-p...)
Affinity DataIC50: 150nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075659(2-(3,3-Dimethyl-but-1-ynyl)-3-(4-methanesulfonyl-p...)
Affinity DataIC50: 5.20E+3nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075659(2-(3,3-Dimethyl-but-1-ynyl)-3-(4-methanesulfonyl-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed