BDBM50075665 3-(4-Methanesulfonyl-phenyl)-2-(4-methyl-pyridin-3-yl)-cyclopent-2-enone::CHEMBL276976

SMILES Cc1ccncc1C1=C(CCC1=O)c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=KAMSHHHKVKJGLB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075665   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075665(3-(4-Methanesulfonyl-phenyl)-2-(4-methyl-pyridin-3...)
Affinity DataIC50: 440nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075665(3-(4-Methanesulfonyl-phenyl)-2-(4-methyl-pyridin-3...)
Affinity DataIC50: 450nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075665(3-(4-Methanesulfonyl-phenyl)-2-(4-methyl-pyridin-3...)
Affinity DataIC50: 4.10E+3nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 (hCOX-1) in the human whole blood assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075665(3-(4-Methanesulfonyl-phenyl)-2-(4-methyl-pyridin-3...)
Affinity DataIC50: 5.50E+3nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed