BDBM50075713 1-(3-Bromo-4,5-dimethoxy-phenyl)-7-chloro-3-[4-(2-hydroxy-ethyl)-piperazine-1-carbonyl]-naphthalene-2-carboxylic acid methyl ester::CHEMBL26441

SMILES COC(=O)c1c(cc2ccc(Cl)cc2c1-c1cc(Br)c(OC)c(OC)c1)C(=O)N1CCN(CCO)CC1

InChI Key InChIKey=LLRLIIOQJHJNCZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075713   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50075713(1-(3-Bromo-4,5-dimethoxy-phenyl)-7-chloro-3-[4-(2-...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE V), isolated from cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50075713(1-(3-Bromo-4,5-dimethoxy-phenyl)-7-chloro-3-[4-(2-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against phosphodiesterase 1 (PDE I), isolated from cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50075713(1-(3-Bromo-4,5-dimethoxy-phenyl)-7-chloro-3-[4-(2-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase 3 (PDE 3) isolated from cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed