BDBM50075965 CHEMBL3415613

SMILES OC(=O)C([O-])=O.C[NH+](CC#C)CC(=C)c1cccc(COc2ccccc2)c1

InChI Key InChIKey=KVUPPSMMDMMNDT-UHFFFAOYSA-O

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075965   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
A* Star

Curated by ChEMBL
LigandPNGBDBM50075965(CHEMBL3415613)
Affinity DataIC50:  400nMAssay Description:Inhibition of human recombinant MAO-B expressed in Sf9 cells using 5-phenylacetaldehyde substrate assessed as hydrogen peroxide production after 1 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
A* Star

Curated by ChEMBL
LigandPNGBDBM50075965(CHEMBL3415613)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant MAO-A expressed in Sf9 cells using 5-hydroxytryptamine substrate assessed as hydrogen peroxide production after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
A* Star

Curated by ChEMBL
LigandPNGBDBM50075965(CHEMBL3415613)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of rat brain MAO-A in nuclei-free homogenates using [14C]hydroxytryptamine substrate after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
A* Star

Curated by ChEMBL
LigandPNGBDBM50075965(CHEMBL3415613)
Affinity DataIC50:  400nMAssay Description:Inhibition of rat brain MAO-B in nuclei-free homogenates using [14C]phenylacetaldehyde substrate after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed