BDBM50076314 5-(4-Chloro-phenyl)-2,2-dimethyl-2,3-dihydro-1H,5H-6-oxa-1-aza-chrysen-4-one::CHEMBL286662

SMILES CC1(C)CC(=O)c2c(N1)ccc1-c3ccccc3OC(c3ccc(Cl)cc3)c21

InChI Key InChIKey=ULQQAJOXIKLWSL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076314   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076314(5-(4-Chloro-phenyl)-2,2-dimethyl-2,3-dihydro-1H,5H...)
Affinity DataKi:  25nMAssay Description:Compound was evaluated for its binding affinity against baculovirus expressed Progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076314(5-(4-Chloro-phenyl)-2,2-dimethyl-2,3-dihydro-1H,5H...)
Affinity DataIC50:  376nMAssay Description:Antagonistic activity by cotransfection assay against human Progesterone receptor in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed