BDBM50076393 (1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-cyclopropanecarboxylic acid::CHEMBL39573

SMILES N[C@@H]([C@@H]1[C@H]([C@@H]1c1ccccc1)C(O)=O)C(O)=O

InChI Key InChIKey=IFLWVSHRWAIVQF-KATARQTJSA-N

Data  2 KI  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50076393   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50076393((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)
Affinity DataKi:  5.00E+4nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor mGluR4aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50076393((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)
Affinity DataKi: >2.70E+5nMAssay Description:Binding affinity towards metabotropic glutamate receptor mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50076393((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)
Affinity DataEC50:  1.56E+5nMAssay Description:Effective concentration of compound against forskolin-stimulated cAMP formation in BHK cells expressing mGluR2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50076393((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)
Affinity DataIC50:  8.00E+3nMAssay Description:Concentration required for the half-maximal inhibition of cAMP hydrolysis in BHK cells expressing mGluR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50076393((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)
Affinity DataEC50: >3.00E+5nMAssay Description:Concentration required for half-maximal stimulation of PI hydrolysis in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50076393((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)
Affinity DataIC50: >3.00E+5nMAssay Description:Concentration required for the half-maximal inhibition of PI hydrolysis in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50076393((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-phenyl-c...)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibitory activity of the compound against Metabotropic glutamate receptor 2 in the rat HEK 293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed