BDBM50076496 17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-methoxy-6,7:2',3'-indolmorphinan::CHEMBL296230

SMILES COc1ccc2C[C@@H]3[C@@H]4Cc5c(C[C@]4(CCN3CC3CC3)c2c1O)[nH]c1ccccc51

InChI Key InChIKey=ZCFDNOOYINVEBV-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50076496   

TargetDelta-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076496(17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-met...)
Affinity DataKi:  7nMAssay Description:Binding affinity towards Opioid receptor delta 1 by the displacement of [3H]DADLE radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076496(17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-met...)
Affinity DataKi:  22nMAssay Description:Ability to inhibit GTP-gamma-S binding to Opioid receptor delta 1 of guinea pig caudateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076496(17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-met...)
Affinity DataKi: >1.25E+3nMAssay Description:Ability to inhibit GTP-gamma-S binding to Opioid receptor kappa 1 of guinea pig caudateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076496(17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-met...)
Affinity DataKi: >1.25E+3nMAssay Description:Ability to inhibit GTP-gamma-S binding to Opioid receptor mu 1 of guinea pig caudate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076496(17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-met...)
Affinity DataKi:  7.92E+3nMAssay Description:Binding affinity towards Opioid receptor kappa 1 by the displacement of [3H]U-69593 radioligand in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50076496(17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-met...)
Affinity DataKi:  1.33E+4nMAssay Description:Binding affinity towards Opioid receptor mu 1 by the displacement of [3H]DAMGO radioligand in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed