BDBM50076878 5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-2-trifluoromethyl-thiazole::CHEMBL17047

SMILES CS(=O)(=O)c1ccc(cc1)-c1nc(sc1-c1ccc(F)cc1)C(F)(F)F

InChI Key InChIKey=IPSWLWPSIVTXOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076878   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076878(5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human cyclooxygenase-2 (hCOX-2) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076878(5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of human cyclooxygenase-1 (hCOX-1) enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed