BDBM50076995 (6S,9R,10S)-10-Hydroxycarbamoyl-9-isobutyl-6-methylcarbamoyl-8-oxo-1,7diaza-cyclotridecane-1-carboxylic acid tert-butyl ester::10-Hydroxycarbamoyl-9-isobutyl-6-methylcarbamoyl-8-oxo-1,7diaza-cyclotridecane-1-carboxylic acid tert-butyl ester::CHEMBL23725

SMILES CNC(=O)[C@@H]1CCCCN(CCC[C@@H]([C@@H](CC(C)C)C(=O)N1)C(=O)NO)C(=O)OC(C)(C)C

InChI Key InChIKey=SXCBCJFEHSPGNX-KSZLIROESA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50076995   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076995((6S,9R,10S)-10-Hydroxycarbamoyl-9-isobutyl-6-methy...)
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-9 (matrix metalloprotease-9, gelatinase B)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076995((6S,9R,10S)-10-Hydroxycarbamoyl-9-isobutyl-6-methy...)
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-9.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076995((6S,9R,10S)-10-Hydroxycarbamoyl-9-isobutyl-6-methy...)
Affinity DataKi: <1nMAssay Description:In vitro inhibition of human MMP-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076995((6S,9R,10S)-10-Hydroxycarbamoyl-9-isobutyl-6-methy...)
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-1 (human fibroblast collagenase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076995((6S,9R,10S)-10-Hydroxycarbamoyl-9-isobutyl-6-methy...)
Affinity DataKi:  3nMAssay Description:Inhibition of MMP-3 (human fibroblast stromelysin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076995((6S,9R,10S)-10-Hydroxycarbamoyl-9-isobutyl-6-methy...)
Affinity DataKi:  3nMAssay Description:Inhibition of human MMP-3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076995((6S,9R,10S)-10-Hydroxycarbamoyl-9-isobutyl-6-methy...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of LPS-stimulated TNF-alpha release in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed