BDBM50077028 CHEMBL3416692

SMILES CCCC[C@H](N)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1

InChI Key InChIKey=HNWIOZGMMTUVKP-LSYYVWMOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50077028   

TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
National Center For Scientific Research&Quot;Demokritos&Quot

Curated by ChEMBL
LigandPNGBDBM50077028(CHEMBL3416692)
Affinity DataIC50:  105nMAssay Description:Inhibition of human recombinant IRAP expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-leucine-7-amido-4-methyl coumarin as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
National Center For Scientific Research&Quot;Demokritos&Quot

Curated by ChEMBL
LigandPNGBDBM50077028(CHEMBL3416692)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human recombinant ERAP2 expressed in baculovirus infected cabbage looper ovary Hi5 cells using L-arginyl-7-amido-4-methyl coumarin as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
National Center For Scientific Research&Quot;Demokritos&Quot

Curated by ChEMBL
LigandPNGBDBM50077028(CHEMBL3416692)
Affinity DataIC50:  920nMAssay Description:Inhibition of human recombinant ERAP1 expressed in baculovirus infected Sf9 cells using L-leucine-7-amido-4-methyl coumarin as substrate after 5 to 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor antagonist protein(Mus musculus)
National Center For Scientific Research&Quot;Demokritos&Quot

Curated by ChEMBL
LigandPNGBDBM50077028(CHEMBL3416692)
Affinity DataIC50:  52nMAssay Description:Inhibition of mouse recombinant IRAP using L-leucine-7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed