BDBM50077099 CHEMBL436344::Trans-6,7-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one

SMILES C[C@H]1CNc2cc3[nH]c(=O)cc(c3cc2C1C)C(F)(F)F

InChI Key InChIKey=GRGCFVNQPFBNIA-JAMMHHFISA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077099   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077099(CHEMBL436344 | Trans-6,7-Dimethyl-4-trifluoromethy...)
Affinity DataKi:  16nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077099(CHEMBL436344 | Trans-6,7-Dimethyl-4-trifluoromethy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells was determined as a function of maximal inhibition of dihydrotestosterone u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077099(CHEMBL436344 | Trans-6,7-Dimethyl-4-trifluoromethy...)
Affinity DataEC50:  10nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed