BDBM50077150 (R)-3-(1H-Indol-3-yl)-2-[4-(4-methoxy-phenylethynyl)-3-nitro-benzenesulfonylamino]-propionic acid::CHEMBL297793

SMILES COc1ccc(cc1)C#Cc1ccc(cc1[N+]([O-])=O)S(=O)(=O)N[C@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI Key InChIKey=YOMOCOIGEKGJBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077150   

Target72 kDa type IV collagenase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50077150((R)-3-(1H-Indol-3-yl)-2-[4-(4-methoxy-phenylethyny...)
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against Matrix metalloprotease-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50077150((R)-3-(1H-Indol-3-yl)-2-[4-(4-methoxy-phenylethyny...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against Matrix metalloprotease-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed