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BDBM50077235 CHEMBL28418::N-[4-(3-Chloro-4-fluoro-phenylamino)-pyrido[3,2-d]pyrimidin-6-yl]-acrylamide

SMILES: Fc1ccc(Nc2ncnc3ccc(NC(=O)C=C)nc23)cc1Cl

InChI Key: InChIKey=KXLRVRIKQJRVCZ-UHFFFAOYSA-N

Data: 6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50077235
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM50077235 (N-[4-(3-Chloro-4-fluoro-phenylamino)-pyrido[3,2-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50077235 (N-[4-(3-Chloro-4-fluoro-phenylamino)-pyrido[3,2-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50077235 (N-[4-(3-Chloro-4-fluoro-phenylamino)-pyrido[3,2-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50077235 (N-[4-(3-Chloro-4-fluoro-phenylamino)-pyrido[3,2-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50077235 (N-[4-(3-Chloro-4-fluoro-phenylamino)-pyrido[3,2-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50077235 (N-[4-(3-Chloro-4-fluoro-phenylamino)-pyrido[3,2-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair