BDBM50077241 CHEMBL53555::N-[4-(3-Chloro-4-fluoro-phenylamino)-pyrido[3,4-d]pyrimidin-6-yl]-acrylamide

SMILES: Fc1ccc(Nc2ncnc3cnc(NC(=O)C=C)cc23)cc1Cl

InChI Key: InChIKey=CIGSBJHMSOROSY-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Human)	BDBM50077241 (N-[4-(3-Chloro-4-fluoro-phenylamino)-pyrido[3,4-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50077241 (N-[4-(3-Chloro-4-fluoro-phenylamino)-pyrido[3,4-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM50077241 (N-[4-(3-Chloro-4-fluoro-phenylamino)-pyrido[3,4-d]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.770	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair