BDBM50077245 CHEMBL297968::N-(4-m-Tolylamino-quinazolin-7-yl)-acrylamide

SMILES Cc1cccc(Nc2ncnc3cc(NC(=O)C=C)ccc23)c1

InChI Key InChIKey=FAGJCAQBJKSOOS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077245   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077245(CHEMBL297968 | N-(4-m-Tolylamino-quinazolin-7-yl)-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of phosphorylation of glutamic acid/tyrosine random copolymer by isolated epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077245(CHEMBL297968 | N-(4-m-Tolylamino-quinazolin-7-yl)-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of epidermal growth factor receptor in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed