BDBM50077343 CHEMBL294437::[3-Methyl-4-(4-nitro-phenyl)-7-oxo-7H-isoxazolo[3,4-d]pyridazin-6-yl]-acetic acid

SMILES C[c-]1[o+]nc2c1c(nn(CC(O)=O)c2=O)-c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=OYTOMQJMIFESGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077343   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50077343(CHEMBL294437 | [3-Methyl-4-(4-nitro-phenyl)-7-oxo-...)
Affinity DataIC50:  4.76E+3nMAssay Description:In vitro inhibitory activity against Aldose reductase 2 obtained from calf lensesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed