BDBM50077348 CHEMBL55614::[3-Methyl-7-oxo-4-phenyl-2-(5-trifluoromethyl-benzothiazol-2-yl)-1,7-dihydro-pyrrolo[2,3-d]pyridazin-6-yl]-acetic acid

SMILES Cc1c(nc2c(O)n(CC(O)=O)nc(-c3ccccc3)c12)-c1nc2cc(ccc2s1)C(F)(F)F

InChI Key InChIKey=NDXKEYHXUXSEBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077348   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bovine)
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50077348([3-Methyl-7-oxo-4-phenyl-2-(5-trifluoromethyl-benz...)
Affinity DataIC50: 9.79E+4nMAssay Description:In vitro inhibitory activity against Aldose reductase 2 obtained from calf lensesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed