BDBM50077397 (R)-2-(4-Phenoxy-benzenesulfonyl)-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid::CHEMBL443478

SMILES OC(=O)[C@H]1Cc2c(CN1S(=O)(=O)c1ccc(Oc3ccccc3)cc1)[nH]c1ccccc21

InChI Key InChIKey=YDDLGJKZEJWWDF-HSZRJFAPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077397   

TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077397((R)-2-(4-Phenoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against human matrix metalloproteinase-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077397((R)-2-(4-Phenoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077397((R)-2-(4-Phenoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory concentration of the compound against human matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed