BDBM50077446 CHEMBL55453::[(R)-2-(2-Biphenyl-4-yl-ethanesulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-yl]-oxo-acetic acid

SMILES OC(=O)C(=O)[C@H]1Cc2ccccc2CN1S(=O)(=O)CCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=XTRJAENNSAJIAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50077446   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077446([(R)-2-(2-Biphenyl-4-yl-ethanesulfonyl)-1,2,3,4-te...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed