BDBM50077538 (R)-3-Methyl-7-nitro-1,2,3,4-tetrahydro-isoquinoline::(R)-3-methyl-7-nitro-1,2,3,4-tetrahydroisoquinoline::CHEMBL304872

SMILES C[C@@H]1Cc2ccc(cc2CN1)[N+]([O-])=O

InChI Key InChIKey=OTVSEAHLIUCIKT-SSDOTTSWSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50077538   

TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50077538((R)-3-Methyl-7-nitro-1,2,3,4-tetrahydro-isoquinoli...)
Affinity DataKi:  250nMAssay Description:In vitro inhibition of PNMT (Phenylethanolamine N-Methyltransferase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50077538((R)-3-Methyl-7-nitro-1,2,3,4-tetrahydro-isoquinoli...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of bovine adrenal Phenylethanolamine N-MethyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50077538((R)-3-Methyl-7-nitro-1,2,3,4-tetrahydro-isoquinoli...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human PNMT by radiochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50077538((R)-3-Methyl-7-nitro-1,2,3,4-tetrahydro-isoquinoli...)
Affinity DataKi:  2.77E+3nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50077538((R)-3-Methyl-7-nitro-1,2,3,4-tetrahydro-isoquinoli...)
Affinity DataKi:  1.38E+4nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed