BDBM50077549 1-{4-[3-(4-Chloro-phenyl)-prop-2-ynyloxy]-[1,2,5]thiadiazol-3-yl}-4-aza-tricyclo[2.2.1.0*2,6*]heptane::CHEMBL60101

SMILES Clc1ccc(cc1)C#CCOc1nsnc1C12CN3CC1C2C3

InChI Key InChIKey=JVDFDVTZQWJMQV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077549   

TargetMuscarinic acetylcholine receptor M2(Rat)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50077549(1-{4-[3-(4-Chloro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...)
Affinity DataIC50: 63nMAssay Description:Inhibition of [3H]- Oxo-M binding at Muscarinic acetylcholine receptor M2 in rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50077549(1-{4-[3-(4-Chloro-phenyl)-prop-2-ynyloxy]-[1,2,5]t...)
Affinity DataEC50:  1.21E+3nMAssay Description:Compound was tested for its potency at M-2 receptor by inhibiting forskolin induced c-AMP formation in CHO-M2 cells human M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed