BDBM50077734 5-Amino-1H-[1,2,4]triazole-3-carboxylic acid {(S)-1-[(S)-1-((S)-1-carbamoyl-2-thiophen-2-yl-ethylcarbamoyl)-4-guanidino-butylcarbamoyl]-2-cyclohexyl-ethyl}-amide::CHEMBL284474

SMILES: NC(=N)NCCC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1nnc(N)[nH]1)C(=O)N[C@@H](Cc1cccs1)C(N)=O

InChI Key: InChIKey=XFJZFBHOWPXHGA-BZSNNMDCSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50077734 (5-Amino-1H-[1,2,4]triazole-3-carboxylic acid {(S)-...) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1nnc(N)[nH]1)C(=O)N[C@@H](Cc1cccs1)C(N)=O Show InChI InChI=1S/C25H39N11O4S/c26-19(37)17(13-15-8-5-11-41-15)32-21(38)16(9-4-10-30-24(27)28)31-22(39)18(12-14-6-2-1-3-7-14)33-23(40)20-34-25(29)36-35-20/h5,8,11,14,16-18H,1-4,6-7,9-10,12-13H2,(H2,26,37)(H,31,39)(H,32,38)(H,33,40)(H4,27,28,30)(H3,29,34,35,36)/t16-,17-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin				Bioorg Med Chem Lett 9: 1423-8 (1999) Article DOI: 10.1016/s0960-894x(99)00197-3 BindingDB Entry DOI: 10.7270/Q2R78DFP
					More data for this Ligand-Target Pair
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50077734 (5-Amino-1H-[1,2,4]triazole-3-carboxylic acid {(S)-...) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1nnc(N)[nH]1)C(=O)N[C@@H](Cc1cccs1)C(N)=O Show InChI InChI=1S/C25H39N11O4S/c26-19(37)17(13-15-8-5-11-41-15)32-21(38)16(9-4-10-30-24(27)28)31-22(39)18(12-14-6-2-1-3-7-14)33-23(40)20-34-25(29)36-35-20/h5,8,11,14,16-18H,1-4,6-7,9-10,12-13H2,(H2,26,37)(H,31,39)(H,32,38)(H,33,40)(H4,27,28,30)(H3,29,34,35,36)/t16-,17-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin				Bioorg Med Chem Lett 9: 1423-8 (1999) Article DOI: 10.1016/s0960-894x(99)00197-3 BindingDB Entry DOI: 10.7270/Q2R78DFP
					More data for this Ligand-Target Pair