BDBM50077979 4-[5-(4-Fluoro-phenyl)-2-piperidin-3-yl-3H-imidazol-4-yl]-pyridine::CHEMBL67874

SMILES Fc1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)C1CCCNC1

InChI Key InChIKey=KLRATASOGXHMKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077979   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077979(4-[5-(4-Fluoro-phenyl)-2-piperidin-3-yl-3H-imidazo...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against recombinant human RAF proto-oncogene serine/threonine-protein kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077979(4-[5-(4-Fluoro-phenyl)-2-piperidin-3-yl-3H-imidazo...)
Affinity DataIC50: 140nMAssay Description:Inhibition of c-Jun N-terminal kinase 2-alpha 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed