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BDBM50078134 2-{3-[(1-Amino-2-phenyl-ethyl)-hydroxy-phosphinoyl]-2-benzyl-propionylamino}-3-phenyl-propionic acid::CHEMBL39422

SMILES: OC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(O)C(=N)Cc1ccccc1

InChI Key: InChIKey=STGYGMSMDRDKDO-UHFFFAOYSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078134   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50078134
PNG
(2-{3-[(1-Amino-2-phenyl-ethyl)-hydroxy-phosphinoyl...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(O)C(=N)Cc1ccccc1
Show InChI InChI=1S/C27H31N2O5P/c28-25(18-22-14-8-3-9-15-22)35(33,34)19-23(16-20-10-4-1-5-11-20)26(30)29-24(27(31)32)17-21-12-6-2-7-13-21/h1-15,23-24,28,33-35H,16-19H2,(H,29,30)(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
2.90n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for A+B stereoisomer)


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50078134
PNG
(2-{3-[(1-Amino-2-phenyl-ethyl)-hydroxy-phosphinoyl...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(O)C(=N)Cc1ccccc1
Show InChI InChI=1S/C27H31N2O5P/c28-25(18-22-14-8-3-9-15-22)35(33,34)19-23(16-20-10-4-1-5-11-20)26(30)29-24(27(31)32)17-21-12-6-2-7-13-21/h1-15,23-24,28,33-35H,16-19H2,(H,29,30)(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
200n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for C+D stereoisomer)


Citation and Details
More data for this
Ligand-Target Pair