BDBM50078802 CHEMBL301594::N-methyl-N-(2-phenylethyl)-5-(phenylsulfamoyl)-2,3-dihydro-1H-indole-1-carboxamide

SMILES CN(CCc1ccccc1)C(=O)N1CCc2cc(ccc12)S(=O)(=O)Nc1ccccc1

InChI Key InChIKey=MVLVGDKGZLAWDS-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078802   

TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078802(N-methyl-N-(2-phenylethyl)-5-(phenylsulfamoyl)-2,3...)
Affinity DataEC50:  55nMAssay Description:In vitro agonistic activity against cloned human beta-3 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078802(N-methyl-N-(2-phenylethyl)-5-(phenylsulfamoyl)-2,3...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro binding affinity towards cloned human beta-2 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078802(N-methyl-N-(2-phenylethyl)-5-(phenylsulfamoyl)-2,3...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro binding affinity towards cloned human beta-1 adrenergic receptor using [125I]iodocyanopindolol as radioligand to stimulate increase in cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed