BDBM50079064 4-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-ylamino)-benzenesulfonamide::CHEMBL91420

SMILES NS(=O)(=O)c1ccc(NN2C(=O)c3cccnc3C2=O)cc1

InChI Key InChIKey=SCWCDACSVVCEME-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079064   

TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50079064(4-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-y...)
Affinity DataKi:  275nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50079064(4-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-y...)
Affinity DataKi:  300nMAssay Description:Inhibitory activity against bovine lung microsomes carbonic anhydrase isozyme IV (bCA IV).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50079064(4-(5,7-Dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-y...)
Affinity DataKi:  2.15E+4nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase isozyme I (hCA I, cytosolic form).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2012
Entry Details Article
PubMed