BDBM50080399 (2R,3R,4S,5R)-2-[6-((1R,2R)-2-Hydroxy-cyclopentylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol::CHEMBL116903

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@@H]3CCC[C@H]3O)ncnc12

InChI Key InChIKey=GYWXTRVEUURNEW-UHFFFAOYSA-N

Data  2 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50080399   

TargetAdenosine receptor A1(Rat)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080399((2R,3R,4S,5R)-2-[6-((1R,2R)-2-Hydroxy-cyclopentyla...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]R-PIA from adenosine A1 receptor of Wistar rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50080399((2R,3R,4S,5R)-2-[6-((1R,2R)-2-Hydroxy-cyclopentyla...)
Affinity DataIC50: 4.40nMAssay Description:Agonist activity at human Adenosine A1 receptor transfected in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50080399((2R,3R,4S,5R)-2-[6-((1R,2R)-2-Hydroxy-cyclopentyla...)
Affinity DataIC50: 28nMAssay Description:Agonist activity at human Adenosine A3 receptor transfected in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50080399((2R,3R,4S,5R)-2-[6-((1R,2R)-2-Hydroxy-cyclopentyla...)
Affinity DataEC50:  631nMAssay Description:Agonist activity at human Adenosine A1 receptor expressed in yeast cells coexpressed with chimeric GPA1/Galphai1 after 16 hrs by beta galactosidase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080399((2R,3R,4S,5R)-2-[6-((1R,2R)-2-Hydroxy-cyclopentyla...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]-CGS- 21680 from adenosine A2A receptor of rat striatal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed