BDBM50080818 (-)-lobeline::2-(6-(2-Hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl)-1-phenylethanone::2-(6-(beta-Hydroxyphenethyl)-1-methyl-2-piperidyl)acetophenone::2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone::8,10-Diphenyllobelionol::CHEMBL122270::Lobelin::Lobnico::alpha-Lobeline

SMILES: CN1[C@@H](CCC[C@@H]1CC(=O)c2ccccc2)C[C@@H](c3ccccc3)O

InChI Key: InChIKey=MXYUKLILVYORSK-UHFFFAOYSA-N

Data: 16 KI  2 IC50

PDB links: 9 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50080818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Synaptic vesicular amine transporter (Mouse)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	381	n/a	n/a	n/a	n/a	n/a	n/a
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Synaptic vesicular amine transporter (Human)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Soluble acetylcholine receptor (California sea hare)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		2.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Synaptic vesicular amine transporter (Rat)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Human)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		5.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Synaptic vesicular amine transporter (Rat)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholine-binding protein (Great pond snail)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Synaptic vesicular amine transporter (Human)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		1.84E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Synaptic vesicular amine transporter (Human)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Synaptic vesicular amine transporter (Rat)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Synaptic vesicular amine transporter (Rat)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Synaptic vesicular amine transporter (Rat)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Synaptic vesicular amine transporter (Rat)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Synaptic vesicular amine transporter (Rat)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		6.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Neuronal acetylcholine receptor subunit alpha-7 (Rat)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		6.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Neuronal acetylcholine receptor subunit alpha-7 (Human)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Synaptic vesicular amine transporter (Human)	BDBM50080818 ((-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-me...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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