BDBM50080895 CHEMBL311198::N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-oxo-2-thiazol-2-yl-ethyl]-2-[(S)-2-naphthalen-2-ylmethyl-3,6-dioxo-4-(3-phenyl-propyl)-piperazin-1-yl]-acetamide

SMILES NC(=N)N1CCCC(C[C@H](NC(=O)CN2[C@@H](Cc3ccc4ccccc4c3)C(=O)N(CCCc3ccccc3)CC2=O)C(=O)c2nccs2)C1

InChI Key InChIKey=RDLVGARUIUOEQM-JQIIOYNJSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50080895   

TargetSerine protease 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50080895(CHEMBL311198 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity of the compound against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50080895(CHEMBL311198 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity of the compound against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50080895(CHEMBL311198 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibitory activity of the compound against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50080895(CHEMBL311198 | N-[(S)-1-(1-Carbamimidoyl-piperidin...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity of the compound against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed