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BDBM50081150 7-Chloro-3-(3,5-dimethyl-phenyl)-6-nitro-4-((S)-2-pyrrolidin-2-yl-ethoxy)-1H-quinolin-2-one::CHEMBL313501::CHEMBL328063

SMILES: Cc1cc(C)cc(c1)-c1c(OCCC2CCCN2)c2cc(c(Cl)cc2[n-]c1=[OH+])[N+]([O-])=O

InChI Key: InChIKey=CHQBMOWBXUMZQU-UHFFFAOYNA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081150   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50081150
PNG
(7-Chloro-3-(3,5-dimethyl-phenyl)-6-nitro-4-((S)-2-...)
Show SMILES Cc1cc(C)cc(c1)-c1c(OCCC2CCCN2)c2cc(c(Cl)cc2[n-]c1=[OH+])[N+]([O-])=O
Show InChI InChI=1/C23H24ClN3O4/c1-13-8-14(2)10-15(9-13)21-22(31-7-5-16-4-3-6-25-16)17-11-20(27(29)30)18(24)12-19(17)26-23(21)28/h8-12,16,25H,3-7H2,1-2H3,(H,26,28)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for Gonadotropin-releasing hormone receptor in rat pituitary membrane at 10 buserelin as radioligand


Bioorg Med Chem Lett 9: 2621-4 (1999)


Article DOI: 10.1016/s0960-894x(99)00447-3
BindingDB Entry DOI: 10.7270/Q2PN94VN
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50081150
PNG
(7-Chloro-3-(3,5-dimethyl-phenyl)-6-nitro-4-((S)-2-...)
Show SMILES Cc1cc(C)cc(c1)-c1c(OCCC2CCCN2)c2cc(c(Cl)cc2[n-]c1=[OH+])[N+]([O-])=O
Show InChI InChI=1/C23H24ClN3O4/c1-13-8-14(2)10-15(9-13)21-22(31-7-5-16-4-3-6-25-16)17-11-20(27(29)30)18(24)12-19(17)26-23(21)28/h8-12,16,25H,3-7H2,1-2H3,(H,26,28)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for Gonadotropin-releasing hormone receptor in rat pituitary membrane at 10 buserelin as radioligand


Bioorg Med Chem Lett 9: 2621-4 (1999)


Article DOI: 10.1016/s0960-894x(99)00447-3
BindingDB Entry DOI: 10.7270/Q2PN94VN
More data for this
Ligand-Target Pair