BDBM50081702 5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole::CHEMBL133939

SMILES COc1ccc2[nH]cc(C[C@@H]3CCCN3C)c2c1

InChI Key InChIKey=MKEGUJPBCIXABO-LBPRGKRZSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50081702   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataKi: >9.40E+3nMAssay Description:Compound was tested for binding affinity using [3H]-MDL-100,907 at 5-hydroxytryptamine 2A receptor sites in rat cortical homogenate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50:  1.20E+3nMAssay Description:Binding affinity of the compound against 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50:  140nMAssay Description:Binding affinity of the compound against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50:  680nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(GUINEA PIG)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50:  420nMAssay Description:Binding affinity of the compound against 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50: >8.40E+3nMAssay Description:Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-HT1D receptor of guinea pig substantia nigra.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081702(5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...)
Affinity DataIC50:  5.80E+3nMAssay Description:Binding affinity of the compound against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed